Sildenafil citrate, known worldwide by the brand name Viagra, is a wonder drug that is used mainly for the treatment of erectile dysfunction and even pulmonary arterial hypertension. Sildenafil citrate was originally conceptualized and developed by scientists in Great Britain, and it was then marketed by Pfizer, a pharmaceutical company located in the United States. Sildenafil citrate is called Revatio, and it is intended for patients with pulmonary arterial hypertension.
Just like some medicines that were made initially for another purpose, sildenafil citrate was originally studied for use in patients suffering from high blood pressure (hypertension) and angina pectoris (a common symptom in ischaemic heart disease patients). The first clinical tests have shown that sildenafil citrate had minimal improvements on angina; however, it resulted to a remarkable instance of penile erections. Due to this, Pfizer had decided that they will market sildenafil citrate to the public for treatment of erectile dysfunction issues, rather than the original idea of having it treat angina.
In 1996, sildenafil citrate was patented and then it was approved by the FDA on March 1998. Sildenafil citrate was the very first oral medication that is FDA approved for treating erectile dysfunction in the US. After that, sildenafil citrate (under the brand name Viagra) sales have been very successful, and it reached a whopping $1,934 million in annual sales during 2008. Continue reading